1. Kim WH, Lillehoj HS, Gay CG. Using genomics to identify novel antimicrobials. Rev Sci Tech 2016; 35:95–103.
2. Dürr UH, Sudheendra U, Ramamoorthy A. LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochim Biophys Acta 2006; 1758:1408–25.
3. Papagianni M. Ribosomally synthesized peptides with antimicrobial properties: biosynthesis, structure, function, and applications. Biotechnol Adv 2003; 21:465–99.
4. Sitaram N, Nagaraj R. Host-defense antimicrobial peptides: importance of structure for activity. Curr Pharm Des 2002; 8:727–42.
5. Lee SH, Lillehoj HS, Tuo W, Murphy CA, Hong YH, Lillehoj EP. Parasiticidal activity of a novel synthetic peptide from the core alpha-helical region of NK-lysin. Vet Parasitol 2013; 197:113–21.
6. Reddy K, Yedery R, Aranha C. Antimicrobial peptides: premises and promises. Int J Antimicrob Agents 2004; 24:536–47.
8. Beisswenger C, Bals R. Antimicrobial peptides in lung inflammation. Chem Immunol Allergy 2005; 86:55–71.
9. Engström Y. Induction and regulation of antimicrobial peptides in
Drosophila. Dev Comp Immunol 1999; 23:345–58.
11. Lehrer RI, Ganz T. Antimicrobial peptides in mammalian and insect host defence. Curr Opin Immunol 1999; 11:23–7.
13. Lynn DJ, Lloyd AT, O’Farrelly C.
In silico identification of components of the Toll-like receptor (TLR) signaling pathway in clustered chicken expressed sequence tags (ESTs). Vet Immunol Immunopathol 2003; 93:177–84.
14. Sang Y, Ramanathan B, Minton JE, Ross CR, Blecha F. Porcine liver-expressed antimicrobial peptides, hepcidin and LEAP-2: cloning and induction by bacterial infection. Dev Comp Immunol 2006; 30:357–66.
15. Townes CL, Michailidis G, Hall J. The interaction of the antimicrobial peptide cLEAP-2 and the bacterial membrane. Biochem Biophys Res Commun 2009; 387:500–3.
16. Harwig SS, Waring A, Yang HJ, Cho Y, Tan L, Lehrer RI. Intramolecular disulfide bonds enhance the antimicrobial and lytic activities of protegrins at physiological sodium chloride concentrations. Eur J Biochem 1996; 240:352–7.
17. Ishige T, Hara H, Hirano T, Kono T, Hanzawa K. Characterization and expression of non-polymorphic liver expressed antimicrobial peptide 2: LEAP-2 in the Japanese quail,
Coturnix japonica. Anim Sci J 2016; 87:1182–7.
19. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2
−ΔΔCT method. Methods 2001; 25:402–8.
20. Zhang Y-A, Zou J, Chang C-I, Secombes CJ. Discovery and characterization of two types of liver-expressed antimicrobial peptide 2 (LEAP-2) genes in rainbow trout. Vet Immunol Immunopathol 2004; 101:259–69.
24. Creighton TE. Disulphide bonds and protein stability. BioEssays 1988; 8:57–63.
26. Wanniarachchi YA, Kaczmarek P, Wan A, Nolan EM. Human defensin 5 disulfide array mutants: disulfide bond deletion attenuates antibacterial activity against
Staphylococcus aureus. Biochemistry 2011; 50:8005–17.
28. Hocquellet A, Odaert B, Cabanne C, et al. Structure–activity relationship of human liver-expressed antimicrobial peptide 2. Peptides 2010; 31:58–66.
29. Etmektedir Sİİ. The increase in LEAP-2 mRNA suggests a synergistic probiotics-doxycycline interaction in chickens. Turk J Immunol 2017; 5:5–12.
32. Parachin NS, Mulder KC, Viana AAB, Dias SC, Franco OL. Expression systems for heterologous production of antimicrobial peptides. Peptides 2012; 38:446–56.
33. Li Y. Recombinant production of antimicrobial peptides in
Escherichia coli: a review. Protein Expr Purif 2011; 80:260–7.
34. Patrickios CS, Yamasaki EN. Polypeptide amino acid composition and isoelectric point ii. comparison between experiment and theory. Anal Biochem 1995; 231:82–91.