| Home | Subscription | E-Submission | Sitemap | Contact Us |
top_img
17th_aaap_banner
Asian Australas. J. Anim. Sci > Volume 24(7); 2011 > Article
Asian-Australasian Journal of Animal Sciences 2011;24(7): 905-911. doi: http://dx.doi.org/10.5713/ajas.2011.10432
Polymorphism of Exon 2 of BMP15 Gene and Its Relationship with Litter Size of Two Chinese Goats
Yuqin Wang, Li Yuanxiao, Zhang Nana, Wang zhanbin, Bai Junyan
  Published online 21 June 2011.

ABSTRACT
Polymorphisms of BMP15 gene exon 2 and its relationship with prolificacy of goats were detected by PCR-SSCP and DNA sequencing methods in Chinese two local goat breeds. The results showed that the product amplified by the primers displayed polymorphisms. Three genotypes (AA, BB and AB) were detected in Funiu white goats, and their frequency was 0.071, 0.715, 0.214, respectively. Two genotypes (AB and BB) were detected in Taihang black goats, and their frequency was 0.342 and 0.658, respectively. Sequencing revealed that four mutations (456TG, 466CG, 510CT, 511TC) occurred in genotype BB of Funiu white goat, which resulted in amino acid substitution of V155G and S171P. No mutation was detected in Taihang black goat. The Funiu white goat with genotype BB had 0.91 or 0.82 kids, more than those with AB or AA, respectively. The difference of the least squares means for litter size between BB and AB was not significant (p>0.05) in Taihang black goat. It is concluded that the BMP15 gene may be a major gene which affects the prolificacy in Funiu white goats. This study could provide basic molecular data on the reproductive characteristics of local breeds of Henan province in China, and a scientific basis for the conservation and utilization of those two goat breeds.
Keywords: Bone Morphogenetic Protein 15 (BMP15);Goat;Prolificacy
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
  E-Mail
  Facebook
  Twitter
METRICS
6
CrossRef
0
Scopus
982
View
0
Down
DNA Polymorphism of Insulin-like Growth Factor-binding Protein-3 Gene and Its Association with Cashmere Traits in Cashmere Goats  2012 November;25(11)
Identification of Single Nucleotide Polymorphism of H-FABP Gene and Its Association with Fatness Traits in Chickens  2007 December;20(12)
Polymorphism of Insulin-like Growth Factor Binding Protein-4 Gene in 17 Pig Breeds and Its Relationship with Growth Traits  2007 October;20(10)
DdeI Polymorphism in Coding Region of Goat POU1F1 Gene and Its Association with Production Traits  2007 September;20(9)
Polymorphism of Insulin-like Growth Factor 1 Receptor Gene in 12 Pig Breeds and Its Relationship with Pig Performance Traits  2006 November;19(11)
Editorial Office
Asian-Australasian Association of Animal Production Societies(AAAP)
Room 708 Sammo Sporex, 23, Sillim-ro 59-gil, Gwanak-gu, Seoul
08776, Korea   TEL : +82-2-888-6558    FAX : +82-2-888-6559   
E-mail : jongkha@hotmail.com
About |  Browse Articles |  Current Issue |  For Authors and Reviewers |  Privacy Policy
Copyright © 2014 by Asian-Australasian Journal of Animal Sciences. All rights reserved.                 powerd by m2community