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Mapping a Quantitative Trait Locus for Growth and Backfat on Porcine Chromosome 18 |
X. L. Wu, C. Lee, J. Jiang, Y. L. Peng, S. L. Yang, B. N. Xiao, X. C. Liu, Q. S. Shi |
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Abstract |
A QTL was localized near S0120 on porcine chromosome 18. The QTL was significant (p<0.05) for average daily gain (ADG) of body weight and backfat thickness (BFT). The estimates of additive and dominance effects for the QTL were 0.0135 kg/day (p<0.001) and 0.0138 kg/day (p>0.5) for ADG and 1.6115 mm (p<0.001) and 0.9281 mm (p>0.05) for BFT. The location of this QTL coincided with a few growth hormone pathway genes. This study suggested that a QTL allele probably resulted from a mutation responsible for physiological lipase deficiency favoring obesity. This QTL might be important to obesity as well as growth in pigs. |
Keywords:
Genome Scan; Mixed Models; Backfat; Obesity; Pigs |
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